Directions and Parking

Mission Regional Medical Center is located on 900 South Bryan Road in Mission, Texas.
Click HERE for a general map of the area, or reference the directions below.

From the North (McAllen):
Depart start on SR-336 (North 10th Street) heading South. Make a Right (West) on Frontage to get on US-83. Drive West on US-83 to Mission. Stay on US-83. Make an exit on Bryan Road. Before crossing the Under-pass, make a right turn (North) on FM-396 (South Bryan Road). At the light, make a Right turn (South) to drive over the Under-Pass toward the Hospital. Pass one street light and make a Right turn to the Hospital’s Main Entrance.


From the Northeast (Edinburg):
Get on US-281 and head South. While on US-281 in Pharr, take a Right Turn (West) to McAllen (US-83). Stay on US-83. Make an exit on Bryan Road. Before crossing the Under-pass, make a right turn (North) on FM-396 (South Bryan Road). At the light, make a Right turn (South) to drive over the Under-Pass toward the Hospital. Pass one street light and make a Right turn to the Hospital’s Main Entrance.


From the Northwest (Alton, Palmhurst):
Head South on Conway. Make a Left (East) on FM-495. Drive East until you hit the light on FM-396 (South Bryan Road). Turn right (South) on FM-396 (South Bryan Road). Drive South on FM-396 and Cross the Overpass of US-83. Pass one street light heading South on FM-396. Make a Right turn to the Hospital’s Main Entrance.


From the East (Pharr-San Juan-Alamo):
Get on US-83 and head West to Mission. Stay on US-83. Make an exit on Bryan Road. Before crossing the Under-pass, make a right turn (North) on FM-396 (South Bryan Road). At the light, make a Right turn (South) to drive over the Under-Pass toward the Hospital. Pass one street light and make a Right turn to the Hospital’s Main Entrance.


From the West (La Joya, Penitas):
Get on US-83 and head East to Mission. Stay on US-83. Make an exit on Bryan Road. Before crossing the Under-pass, make a right turn (South) on FM-396 (South Bryan Road). At the light, make a Right turn (South) to South Bryan Road. Make a right turn to the Hospital’s Main Entrance.